What experience do you have with tocilizumab in general in all seriously ill patients? What about the patient who is not a candidate for intubation due to age or comorbidities? Do you think it has a role in slowing down progression in those patients who are doing poorly and can avoid intubation or improve the ARDS picture? When should it be given? Does it make sense to wait for the serious situation with the patient already intubated? / Tocilizumab: IL- 6受体单克隆抗体注射剂。对重症病人使用IL- 6受体单克隆抗体注射剂你们有哪些经验?尤其 是那些由于高龄或者有其他疾病的患者而言。你们认为这个药物可以控制住那些病情恶化的病人的情况么?它可以避免插管或者改善ARDS影像?么?在什么时候应该用药?需要等到病人已经严重到需要插管治疗时在用药么?