COVID-19 workers may be required to undertake night-time, early morning, rotating and extended duration workhours. These work demands may result in insufficientsleep and having to work during the body’s circadian low point in alertness. Together, these factors may result in sleepiness and reduced alertness levels, whichcan have adverse effects on physical and cognitiveperformance and potentially raise the risk of accidents and errors. If prolonged, inadequate sleep and circadian disruption can also have a negative impact on immune function and mental health.