The COVID-19 Host Genetics Initiative

19 Apr, 2020


The COVID-19 host genetics initiative brings together the human genetics community to generate, share and analyze data to learn the genetic determinants of COVID-19 susceptibility, severity and outcomes. Such discoveries could help to generate hypotheses for drug repurposing, identify individuals at unusually high or low risk, and contribute to global knowledge of the biology of SARS-CoV-2 infection and disease.


The COVID-19 host genetics initiative is a bottom-up collaborative effort that has three main aims:

Aim 1: Provide an environment to foster the sharing of resources to facilitate COVID-19 host genetics research (e.g. protocols, questionnaires).

Aim 2: Organize analytical activities across studies to identify genetic determinants of COVID-19 susceptibility and severity.

Aim 3: Provide a platform to share the results from meta-analytical activities to benefit the broader scientific community.

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