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MIS for elective surgery | Ken Campbell
13 Apr, 2020Dr. Ken Campbell gives his lecture about MIS for elective surgery.
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MIS for emergency surgery | Zhongtao Zhang
13 Apr, 2020Dr. Zhongtao Zhang gives his lecture about MIS for emergency surgery.
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FDA Authorizes Blood Purification Device to Treat COVID-19
12 Apr, 2020
The U.S. Food and Drug Administration issued an emergency use authorization for a blood purification system to treat patients 18 years of age or older with confirmed Coronavirus Disease 2019 (COVID-19) admitted to the intensive care unit (ICU) with confirmed or imminent respiratory failure.
The authorized product works by reducing the amount of cytokines and other inflammatory mediators, i.e., small active proteins in the bloodstream that control a cell’s immune respons... -
Screening and Severity of Coronavirus Disease 2019 (COVID-19) in Children in Madrid, Spain
12 Apr, 2020AbstractAs the pandemic of coronavirus disease 2019 (COVID-19) spreads, new data emerge and understanding of the disease improves. Reports associated with children are growing but still scarce. The epicenter of the epidemic has displaced to Europe. The first case in Spain was declared on January 31, 2020, and the first case in the Madrid region was declared on February 27, 2020.
MethodsWith the aim of obtaining an overview of the proportion of confirmed cases among those tested and the sev... -
Projecting the transmission dynamics of SARS-CoV-2 through the post-pandemic period
12 Apr, 2020The Department of Immunology and Infectious Diseases and the Department of Epidemiology of Harvard T.H. Chan School of Public Health write this article projecting the transmission dynamics of SARS-CoV-2 through the post-pandemic period.
Abstract
There is an urgent need to project how transmission of the novel betacoronavirus SARS-CoV-2 will unfold in coming years. These dynamics will depend on seasonality, the duration of immunity, and the strength of cross-immunity to/from the oth... -
Structure of the RNA-dependent RNA polymerase from COVID-19 virus
12 Apr, 2020AbstractA novel coronavirus (COVID-19 virus) outbreak has caused a global pandemic resulting in tens of thousands of infections and thousands of deaths worldwide. The RNA-dependent RNA polymerase (RdRp, also named nsp12) is the central component of coronaviral replication/transcription machinery and appears to be a primary target for the antiviral drug, remdesivir. We report the cryo-EM structure of COVID-19 virus full-length nsp12 in complex with cofactors nsp7 and nsp8 at 2.9-Å resolution. ... -
The only way this ends: herd immunity
12 Apr, 2020Via The Boston Globe, Jeff Howe write: The only way this ends: herd immunityThere is still a lot we don’t know about COVID-19, including exactly how many people are or have been infected, epidemiologists believe that this virus won’t begin to disappear until a far higher percentage of the population — at least 60 percent — develops immunity. If that doesn’t happen with a vaccine, it has to happen through exposure.
For weeks, the most pressing policy challenge has been relieving the life-an... -
How a 100-year-old vaccine for tuberculosis could help fight the novel coronavirus
12 Apr, 2020As researchers scramble to find new drugs and vaccines for Covid-19, a vaccine that is more than a century old has piqued researchers' interests. The Bacillus Calmette-Guerin vaccine -- which was first developed to fight off tuberculosis -- is being studied in clinical trials around the world as a way to fight the novel coronavirus.
Tuberculosis and Covid-19 infection are two very different diseases -- TB is caused by a type of bacteria while Covid-19 is caused by a virus, for starters. Bu... -
The gendered dimensions of COVID-19
12 Apr, 2020SARS-CoV-2 does not discriminate, but without careful consideration, the global response to the COVID-19 pandemic might. Demographic data from small studies are already informing political decisions and clinical research strategies. Women and men are affected by COVID-19, but biology and gender norms are shaping the disease burden. The success of the global response—the ability of both women and men to survive and recover from the pandemic's effects—will depend on the quality of evidence info... -
UK launches massive diagnostic network
12 Apr, 2020
The UK government opened its first mass coronavirus-testing facility on 9 April.
The lab, in Milton Keynes, is the first of three such facilities to open. The others — in Glasgow and Alderley Park in Nether Alderley — are scheduled to open within the next two weeks. In March, the UK government requisitioned polymerase chain reaction machines from university labs across the country in order to outfit these central testing facilities.
The labs — which t... -
Zhongshan Guidance of COVID-19 Prevention and Control
11 Apr, 2020Zhongshan Guidance of COVID-19 Prevention and Control
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Panel Discussion
11 Apr, 2020Panel discussion about minimally invasive surgery during COVID-19 outbreak with Dr. Balibrea as Moderator.