A novel SARS-like coronavirus (SARS-CoV-2) recently emerged and is rapidly spreading in humans1,2. A key to tackling this epidemic is to understand the virus’s receptor recognition mechanism, which regulates its infectivity, pathogenesis and host range. SARS-CoV-2 and SARS-CoV recognize the same receptor - human ACE2 (hACE2)3,4. Here we determined the crystal structure of the SARS-CoV-2 receptor-binding domain (RBD) (engineered to facilitate crystallization) in complex with hACE2. Compared wi...

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Think of the open-source project Nextstrain.org as an outbreak museum. Labs around the world contribute genetic sequences of viruses collected from patients, and Nextstrain uses that data to paint the evolution of epidemics through global maps and phylogenetic charts, the family trees for viruses.

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Human infections with a novel coronavirus (SARS-CoV-2) were first identified via syndromic surveillance in December of 2019 in Wuhan China. Since identification, infections (coronavirus disease-2019; COVID-19) caused by this novel pathogen have spread globally, with more than 250,000 confirmed cases as of March 21, 2020. An open-label clinical trial has just concluded, suggesting improved resolution of viremia with use of two existing therapies: hydroxychloroquine (HCQ) as monotherapy, and in...

Estimating the number of infections and the impact of nonpharmaceutical interventions on COVID-19 in 11 European countriesSummary  - Click to access full textFollowing the emergence of a novel coronavirus (SARS-CoV-2) and its spread outside of China, Europe is now experiencing large epidemics. In response, many European countries have implemented unprecedented non-pharmaceutical interventions including case isolation, the closure of schools and universities, banning of mass gatheri...

AbstractFew novel or emerging infectious diseases have posed such vital ethical challenges so quickly and dramatically as the novel coronavirus SARS‐CoV‐2. The World Health Organization declared a public health emergency of international concern and recently classified COVID‐19 as a worldwide pandemic. As of this writing, the epidemic has not yet peaked in the United States, but community transmission is widespread. President Trump declared a national emergency as fifty governors declared sta...

The goal of the hackathon is to bring together the decentralized artificial intelligence community in an effort to help find new approaches to combat the coronavirus crisis.
Starting April 1st, the Decentralized AI Alliance and partners SingularityNET and Ocean Protocol plan to host an online, not-for-profit hackathon called COVIDathon.

The goal is to bring together the decentralized artificial intelligence community in an effort to help find solutions to combat the COVID-19 outbrea...

An artificial intelligence tool accurately predicted which patients newly infected with the COVID-19 virus would go on to develop severe respiratory disease, a new study found.


Towards an Artificial Intelligence Framework for Data-Driven Prediction of Coronavirus Clinical Severity
AbstractThe virus SARS-CoV2, which causes coronavirus disease (COVID-19) has become a pandemic and has spread to every inhabited continent. Given the increasing caseload, there is an urgent need to aug...

Via Science, Jon Cohen write: Not wearing masks to protect against coronavirus is a ‘big mistake,’ top Chinese scientist says 
Chinese scientists at the front of that country’s outbreak of coronavirus disease 2019 (COVID-19) have not been particularly accessible to foreign media. Many have been overwhelmed trying to understand their epidemic and combat it, and responding to media requests, especially from journalists outside of China, has not been a top priority.

Science has tried t...

It's imperative for hospital IT departments to track information for management decisions, enable the fast ramp-up of additional ICU beds and set up tools for remote working.As the number of lives touched by COVID-19 is continuously mounting, so are the efforts of IT departments to counter the rising pressure on hospitals. The recent HIMSS Webinar, 'Italy and Germany facing COVID-19', hosted by Charles Alessi, Chief Clinical Officer, HIMSS, had two CIOs from private hospital chains in Italy a...

UEG (United European Gastroenterology) did a webinar on Thursday 27th about Covid-19 and Digestive Health. Watch the recorded webinar to learn more about COVID-19, IBD and endoscopy from the experts James Lindsay and Alessandro Repici. You can watch it here. 




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