AbstractA novel coronavirus (COVID-19 virus) outbreak has caused a global pandemic resulting in tens of thousands of infections and thousands of deaths worldwide. The RNA-dependent RNA polymerase (RdRp, also named nsp12) is the central component of coronaviral replication/transcription machinery and appears to be a primary target for the antiviral drug, remdesivir. We report the cryo-EM structure of COVID-19 virus full-length nsp12 in complex with cofactors nsp7 and nsp8 at 2.9-Å resolution. ...

Via The Boston Globe, Jeff Howe write: The only way this ends: herd immunityThere is still a lot we don’t know about COVID-19, including exactly how many people are or have been infected, epidemiologists believe that this virus won’t begin to disappear until a far higher percentage of the population — at least 60 percent — develops immunity. If that doesn’t happen with a vaccine, it has to happen through exposure.
For weeks, the most pressing policy challenge has been relieving the life-an...

As researchers scramble to find new drugs and vaccines for Covid-19, a vaccine that is more than a century old has piqued researchers' interests. The Bacillus Calmette-Guerin vaccine -- which was first developed to fight off tuberculosis -- is being studied in clinical trials around the world as a way to fight the novel coronavirus.
Tuberculosis and Covid-19 infection are two very different diseases -- TB is caused by a type of bacteria while Covid-19 is caused by a virus, for starters. Bu...

SARS-CoV-2 does not discriminate, but without careful consideration, the global response to the COVID-19 pandemic might. Demographic data from small studies are already informing political decisions and clinical research strategies. Women and men are affected by COVID-19, but biology and gender norms are shaping the disease burden. The success of the global response—the ability of both women and men to survive and recover from the pandemic's effects—will depend on the quality of evidence info...

The UK government opened its first mass coronavirus-testing facility on 9 April.




The lab, in Milton Keynes, is the first of three such facilities to open. The others — in Glasgow and Alderley Park in Nether Alderley — are scheduled to open within the next two weeks. In March, the UK government requisitioned polymerase chain reaction machines from university labs across the country in order to outfit these central testing facilities.




The labs — which t...

Imaging COVID-19 AI initiative is a multicenter European project to enhance computed tomography (CT) in the diagnosis of COVID-19 by using artificial intelligence. The project group will create a deep learning model for automated detection and classification of COVID-19 on CT scans, and for assessing disease severity in patients by quantification of lung involvement.



Many different hospitals and institutions across Europe will collaborate to rapidly develop an artificial in...

Imaging COVID-19 AI initiative is a multicenter European project to enhance computed tomography (CT) in the diagnosis of COVID-19 by using artificial intelligence. The project group will create a deep learning model for automated detection and classification of COVID-19 on CT scans, and for assessing disease severity in patients by quantification of lung involvement.









Many different hospitals and institutions across Europe will collaborate to rapidly ...

The diagnosis center of Hospital Clínic de Barcelona has incorporated a new robot to perform massively PCR tests for COVID-19 diagnosis. After calibrational procedures, it is a matter of days that will be operational. This initiative, Covichain Robots, it has been carried out by several public and private organizations, making possible robot's arrival. Being a high tech open-source robot, it can be modified for adapting it to the procedures required in different hospitals. In this particular ...

COVIDWarriors is a non-profit association formed by professionals, senior managers and patrons, from all fields, united in the fight against COVID-19 with 3 objectives:

Gather volunteers: 
Proactive organizations, entrepreneurial talent, technological initiatives, financing in the fight against COVID-19.




Connect:

With the specific needs detected at a logistical, health, social, psychological level...



Accelerate:

Own or already exist...

Collaborative project in 3D-printing personal protection equipment (PPE) for healthcare personnel.




Several of companies from Venezuela - such as 3Dx cub3, En3D Venezuela, or Nedraki - are working together to 3D-print PPE materials and sending them to hospitals. They have already printed 724 visor frames and 5472 facial masks, and 4552 of them have been sent to Healthcare Institutions.




In the project's website you can help them by donating money or mat...

U.S. drugmaker Pfizer Inc (PFE.N) said on Thursday that early data has helped it identify a drug candidate with the potential to help treat patients infected with the novel coronavirus.

It also finalized a plan to develop a coronavirus vaccine in partnership with German drugmaker BioNTech SE (22UAy.F) and said the companies hope to produce millions of vaccines by the end of 2020. The companies said they plan to start trials of the vaccine as early as this month.

Data from pr...

The outbreak of COVID-19 has now become a pandemic. The new coronavirus has affected nearly all continents; at the time of writing, South Korea, Iran, Italy, and other European countries have experienced sharp increases in diagnosed cases. Globalization and increasingly interconnected economies mean most countries will be affected by COVID-19. Global effort is therefore required to break the chains of virus transmission.






Could robots be effective res...