Germany gave the green light for human trials of potential coronavirus vaccines developed by German biotech company BioNTech, which is racing teams in Germany, the U.S. and China to develop an agent that will stop the pandemic.
The trial, only the fourth worldwide of a vaccine targeting the virus, will be initially conducted on 200 healthy people, with more subjects, including some at higher risk from the disease, to be included in a second stage, German vaccines regulator the Paul...
A drug called auranofin, approved for the treatment of rheumatoid arthritis, effectively inhibits severe acute respiratory syndrome coronavirus (SARS-CoV-2) in laboratory conditions, as described in a new study by Georgia State University researchers.
Auranofin is a chemical compound that contains gold particles. Therefore it is also known as a gold-salt compound. Such gold-containing drugs have known anti-inflammatory properties, and this specific triethyl phosphine can reduc...
The number of people officially identified as infected with coronavirus in Italy has fallen for the first time since the country's outbreak began, authorities have said.
As of Monday, there were 108,237 people either being treated in hospital or recovering at home, 20 fewer than the previous day.
Authorities say the small but symbolic drop is a "positive development".
Italy's lockdown continues until 3 May but some businesses have reopened.
The drug giant Novartis said Monday it would conduct a 450-person study to determine if hydroxychloroquine, the malaria drug touted by many pundits and President Trump, can effectively treat Covid-19, the disease caused by the novel coronavirus.
The study will be a randomized, double-blind placebo-controlled study, the medical gold standard in which patients will be assigned one of three options: hydroxychloroquine, the combination of hydroxychloroquine and the antibiot...
The diagnostics startup Curative has received an emergency use authorization from the Food and Drug Administration for its novel test to determine COVID-19 infection.
The company says that its tests have already been used by the City of Los Angeles since late March and have tested over 53,000 city residents.
Curative’s tests use an oral-fluid sample collected by having the subject cough to produce sputum, which release the virus from deep in...
A key portion of a coronavirus protein could form the basis of a safe and effective vaccine.
Coronavirus particles bristle with spiny ‘spike proteins’. A portion of the spike called the receptor-binding domain recognizes and attaches to a molecule found on the surface of many human cells, allowing the viral particle to gain entry into those cells.
Hyeryun Choe and Michael Farzan at the Scripps Research Institute in Jupiter, Florida, and their colleagues immunized rats with f...
Covid-19 patients who are getting an experimental drug called remdesivir have been recovering quickly, with most going home in days, STAT News reported Thursday after it obtained a video of a conversation about the trial.
The patients taking part in a clinical trial of the drug have all had severe respiratory symptoms and fever, but were able to leave the hospital after less than a week of treatment, STAT quoted the doctor leading the trial as saying."The best ...
Swiss drugmaker Roche aims by next month to offer blood tests to identify those who had been infected with the coronavirus, potentially helping inform locked-down nations of who might have some immunity and be able to resume work or contact with the public.
The Basel-based company said on Friday it wants to make the antibody test available by early May in countries that accept European CE regulatory standards, and is seeking U.S. Food and Drug Administration emergency authorizati...0
The US Food and Drug Administration has authorized a saliva test for "emergency use" for diagnosing Covid-19. Rutgers University, where the test was developed in collaboration with other groups, announced the FDA authorization on Tuesday after formally receiving it over the weekend.
Using saliva to diagnose novel coronavirus infections could expand testing capacities across the United States. So far testing for Covid-19 has usually involved nose or throat swabs.
"It means ...
BenevolentAI, a startup which has raised $292 million to apply AI to create drugs faster, today says it has uncovered an already approved drug as a potential treatment for COVID-19, after it applied its AI platform and team to the problem. The revelation, which has now appeared in peer-reviewed scientific journals and has entered clinical trials with a major pharmaceutical company, could offer a glimmer of hope to a world locked down by the pandemic.
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The U.S. Food and Drug Administration issued an emergency use authorization for a blood purification system to treat patients 18 years of age or older with confirmed Coronavirus Disease 2019 (COVID-19) admitted to the intensive care unit (ICU) with confirmed or imminent respiratory failure.
The authorized product works by reducing the amount of cytokines and other inflammatory mediators, i.e., small active proteins in the bloodstream that control a cell’s immu...A small study from China suggests transfusions of blood from those who have beaten the disease could help buy time for new victims
Transfusions of blood serum from people who’ve recovered from covid-19 could help severe cases recover, according to a new study from China.
Plasma donation: The concept of using blood from survivors—or “convalescent plasma”—isn’t new, but it’s now being tried against covid-19 because there aren’t any drugs known to work. A survivor’s blood is c...