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  • Five researchers have created a robot able to conduct 2400 COVID-19 tests everyday

    19 Apr, 2020
    Four robots have been delivered in four Spanish hospitals, including Hospital Clínic of Barcelona and Instituto de Salud Carlos III of Madrid. 
    The five researches have created the anti-COVID19 robot in one room, after 22 days of quarantine. Andreu Veà, one of the creators of the robots, claims that "each robot can perform 2400 PCR tests everyday" and with the four units working together they will achieve 70000 analysis per week.
    Four anti-COVID19 robots were sent last Friday to four Sp...
  • Who's Hit Hardest By COVID-19? Why Obesity, Stress And Race All Matter

    19 Apr, 2020

    As data emerges on the spectrum of symptoms caused by COVID-19, it's clear that people with chronic health conditions are being hit harder.




    While many people experience mild illness, 89% of people with COVID-19 who were sick enough to be hospitalized had at least one chronic condition. About half had high blood pressure and obesity, according to data from the Centers for Disease Control and Prevention. And about a third had diabetes and a third had cardiovascular diseas...
  • Hydroxychloroquine in the management of critically ill patients with COVID-19: the need for an evidence base

    19 Apr, 2020
    With the rapid spread of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), critical care physicians are seeing increasing numbers of patients with acute respiratory failure secondary to coronavirus disease 2019 (COVID-19) and reporting mortality rates of 40–65% for those requiring mechanical ventilation1 —strikingly higher than the mortality rates reported for the more typical acute respiratory distress syndrome associated with other diseases. The focus of ther...
  • Temporal dynamics in viral shedding and transmissibility of COVID-19

    19 Apr, 2020
    AbstractWe report temporal patterns of viral shedding in 94 patients with laboratory-confirmed COVID-19 and modeled COVID-19 infectiousness profiles from a separate sample of 77 infector–infectee transmission pairs. We observed the highest viral load in throat swabs at the time of symptom onset, and inferred that infectiousness peaked on or before symptom onset. We estimated that 44% (95% confidence interval, 25–69%) of secondary cases were infected during the index cases’ presymptomatic stag...
  • China Raises Coronavirus Death Toll by 50% in Wuhan

    18 Apr, 2020

    China on Friday raised its coronavirus death toll by 50 percent in Wuhan, the city where the outbreak first emerged, amid accusations that the government had concealed the extent of the epidemic.

    Officials placed the new tally at 3,869 deaths from the coronavirus in the central Chinese city, an increase of 1,290 from the previous figure. The number of cumulative confirmed infections in the city was also revised upward to 50,333, an increase of 325.







    Th...
  • Vaccine from viral spikes holds promise

    18 Apr, 2020

    A key portion of a coronavirus protein could form the basis of a safe and effective vaccine.

    Coronavirus particles bristle with spiny ‘spike proteins’. A portion of the spike called the receptor-binding domain recognizes and attaches to a molecule found on the surface of many human cells, allowing the viral particle to gain entry into those cells.

    Hyeryun Choe and Michael Farzan at the Scripps Research Institute in Jupiter, Florida, and their colleagues immunized rats with f...
  • How to Obtain a Nasopharyngeal Swab Specimen - NEJM

    18 Apr, 2020
    Overview
    Collection of specimens from the surface of the respiratory mucosa with nasopharyngeal swabs is a procedure used for the diagnosis of Covid-19 in adults and children. The procedure is also commonly used to evaluate patients with suspected respiratory infection caused by other viruses and some bacteria. This video describes the collection of nasopharyngeal specimens for detection of Covid-19, the illness caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS...
  • Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency

    18 Apr, 2020
    Effective treatments for coronavirus disease 2019 (COVID-19) are urgently needed to control this current pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Replication of SARS-CoV-2 depends on the viral RNA-dependent RNA polymerase (RdRp), which is the likely target of the investigational nucleotide analogue remdesivir (RDV). RDV shows broad-spectrum antiviral activity against RNA viruses, and previous studies with RdRps from Ebola virus (EBOV) and Middle East r...
  • Rates of Co-infection Between SARS-CoV-2 and Other Respiratory Pathogens

    18 Apr, 2020
    Last April 15th, the Journal of the American Medical Association (JAMA) published a research letter relating the Covid-19 infections with other respiratory diseases. 
    As of April 3, 2020, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had caused 972 303 cases of coronavirus disease 2019 (COVID-19) and 50 322 deaths worldwide. Early reports from China suggested that co-infection with other respiratory pathogens was rare. If this were the case, patients positive for other patho...
  • How does coronavirus kill? Clinicians trace a ferocious rampage through the body, from brain to toes

    18 Apr, 2020
    How does coronavirus kill? Clinicians trace a ferocious rampage through the body, from brain to toes



    On rounds in a 20-bed intensive care unit (ICU) one recent day, physician Joshua Denson assessed two patients with seizures, many with respiratory failure and others whose kidneys were on a dangerous downhill slide. Days earlier, his rounds had been interrupted as his team tried, and failed, to resuscitate a young woman whose heart had stopped. All shared one thing, says Denson,...
  • Antibiotic treatment for COVID-19 complications could fuel resistant bacteria

    18 Apr, 2020



    Science’s COVID-19 reporting is supported by the Pulitzer Center.

    In her regular job, Priya Nori runs Montefiore Medical Center’s antibiotic stewardship program, and spends most of her time ensuring that the Bronx-based hospital doesn’t overuse the drugs and allow bacteria resistant to them to thrive. But like many physicians, Nori is now spending all of her time helping treat COVID-19 patients at her New York City hospital, which like other medical centers in the pandemic ...
  • Knowledge Shot: Disinfecting Frequently Touched Surfaces

    17 Apr, 2020
    This video takes the guidelines from CDC regarding how to disinfect frequently touched surfaces in response to COVID-19 pandemic and explain the procedure to prepare a homemade cleaner.